Novel adenovirus vector-based vaccines for HIV-1
نویسندگان
چکیده
منابع مشابه
Design Challenges for HIV-1 Vaccines Based on Humoral Immunity
INTRODUCTION Human Immunodeficiency Virus-1 (HIV1) presents profound challenges to vaccine developers. Potential hurdles of relevance to the design of an effective HIV-1 vaccine based on humoral immunity include: (1) the exceptional rate of mutation of the viral genome due to an error-prone polymerase (i.e., reverse transcriptase) (1), (2) a relatively high rate of genomic recombination (2, 3),...
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ژورنال
عنوان ژورنال: Current Opinion in HIV and AIDS
سال: 2010
ISSN: 1746-630X
DOI: 10.1097/coh.0b013e32833cfe4c